Mosquito allergy is frequent in certain geographic areas that, in turn, have a high prevalence of allergy to dust mites.
The results of this study indicate that a protein shared by mosquitoes and mites, tropomyosin, is responsible for cross-reactivity at both humoral (antibodies) and cellular levels. These results reinforce the interesting possibility that patients allergic to mites may have allergic reactions to mosquitoes by cross-reactivity mechanisms and vice versa.
The study has had the collaboration of INMUNOTEK.
Title:Tropomyosins in mosquito and house dust mite cross-react at the humoral and cellular level.
1 Complutense University of Madrid, Madrid, Spain.
2 Institute for Immunological Research/University of Cartagena, Cartagena, Colombia.
3 Inmunotek S.L., Alcalá de Henares, Spain.
4 University of South Florida College of Medicine, Tampa, Florida.
5 Floridsdorf Allergy Center (FAZ), Vienna, Austria.
6 Allergy Clinic Reumannplatz, Vienna, Austria.
7 Division of Structural Biology, Institute of Molecular Biosciences, BioTechMed University of Graz, Graz, Austria.
8 Department of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria.